Did you know that heart disease is said to be the leading cause of death in America? However, individuals who regularly eat natto (fermented soybean) have a lower risk for cardiovascular diseases, thanks to the nattokinase enzyme in this popular Japanese dish. This enzyme is produced by the bacterium Bacillus subtilis during the fermentation process of natto. Nattokinase is most well-known for its cardiovascular benefits, including clot-dissolving (fibrinolytic) effects. It is often taken for thinning the blood, improving circulation, and decreasing cholesterol. However, some studies suggest that it may also be beneficial for gut health, COPD, and chronic sinusitis.
There are only 2 ways to consume nattokinase: eating natto or taking supplements. Due to their ability to guarantee dosage and potency, nattokinase supplements can be more effective than eating natto – as long as you are using a reliable supplement. While the benefits of a nattokinase supplement can significantly impact health, the market is unfortunately saturated with low quality nattokinase supplements that are inefficient and unhelpful. However, research has shown that high-quality supplements with the correct dosage and potency of nattokinase, can deliver significant results. The bottom line is that there are effective nattokinase supplements that will do what they say they will – you just have to find them.
When choosing a nattokinase supplement, you should be cautious. Many manufacturers of nattokinase supplements make grand promises, only for you to find out later that there is no real change, leaving you with an empty bottle, empty purse, and empty promises. Don’t be dismayed – there are some that really do work! You just need to find a legitimate product.
Key points to consider when choosing a nattokinase supplement
When choosing a nattokinase supplement, you should look for a company with a strong reputation that sells a wide range of nutritional supplements. An effective supplement will be manufactured in an FDA-registered laboratory that adheres to good manufacturing practices (GMP). These certifications help to ensure a product’s purity and quality.
If you come across a company selling nattokinase supplements using strong marketing terms or slogans, or if they are endorsed by famous celebrities, you should stay clear. If the company and product formula don’t speak for themselves, then nothing else should.
Once you have decided that a nattokinase supplement is for you, and you would like to try a top-quality product, check out our reviews for a number of top nattokinase supplements that are currently available on the market. We examined numerous products for their ingredients, consumer feedback, business reputation, and more, in order to help you discover which supplements are the real deal. No more guesswork. We have done all the hard work for you – your search for answers is over!
What makes a nattokinase supplement effective?
The secret is simply in the formula! Using the clinically studied dosage and potency of nattokinase will help achieve results like nothing else. Nattokinase has been studied in dosages of 100 mg with 2,000 FU (fibrin units) and dosages of 200 mg with 4,000 FU. We recommend buying supplements that offer 4,000 FU split into 2 capsules to allow you to adjust your dosage as necessary.
When buying a nattokinase supplement, make sure that it is free of vitamin K2. Natto (the source of nattokinase) naturally contains vitamin K2, but this vitamin is involved in blood clotting and can interact with anticoagulant medications, making it counterproductive to the aims of nattokinase. Additionally, a bioavailability enhancer can be beneficial for ensuring you get the most out of your supplements. For example, BioPerine® is known to enhance nutrient absorption and therefore may improve the efficacy of a nattokinase supplement.
Our recommended choice meets the above qualifications and stands above and beyond the competition. The company’s excellent reputation, high-quality product, and external independent monitoring and testing are enough to earn a high ranking. When you consider all of those factors and its 60-day money-back guarantee policy, Approved Science Nattokinase becomes a product that you are going to want to take a closer look at.
Nattokinase Report
APPROVED

Rating: Excellent

✓ Effectiveness
✓ Potency
✓ Money Back Guarantee
✓ Value
✓ Consumer Feedback
✓ Company Reputation
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Editor’s Choice
Approved Science Nattokinase
If you are looking to improve your overall cardiovascular health with nattokinase, then Approved Science Nattokinase is something that deserves your undivided attention. Of all the nattokinase supplements currently available on the market, this one deserves a closer look and will very likely change your life!
It contains high-quality, clinically-proven ingredients for promoting cardiovascular health and supporting overall health. It was the only product we found that contains a 4000 FU daily serving of nattokinase with BioPerine® for boosting absorption. In addition, vitamin K2 has been removed to avoid contraindications. It does not contain any harmful additives or preservatives and is generally safe.
Quality: Approved Science Nattokinase contains high-grade, natural, clinically-verified ingredients that are GMP-certified and made in an FDA-registered facility.
Reputation: Approved Science’s reputation is top-quality. They are well known in the industry and an established company that provides great customer service, secure and easy checkout as well as prompt, efficient delivery. This manufacturer has several third-party monitoring services, including buySAFE, Norton, and Trustee, as well as an A+ rating from the quality monitoring company QualityTrusted. Approved Science’s commitment to the health industry and consumers is excellent, providing further legitimacy to their products by producing them in an FDA-registered laboratory.
Money-Back Guarantee: Every item sold is supported by a 60-day 100% money-back guarantee. Such guarantees from manufacturers show strong confidence in their products’ ability to deliver results. Great news for consumers.
Bottom Line: If you are looking for a product that ticks all the boxes for an effective nattokinase supplement that comes from an established reputable company with an excellent money-back guarantee, then this is the supplement for you.
It would be good to note that, due to high demand, Approved Science Nattokinase is often sold out. To avoid having to back order, don’t hesitate to make that purchase when you see it in stock.
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Rating: Good

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Allergy Research Group Nattokinase
Our second pick comes from a company called Allergy Research Group that prides itself on the purity of their supplements. Additionally, they produce science-based formulas which is what all supplement companies should do, but many don’t. So how does this formula stack up against the competition?
This product provides the ideal dosage and potency of nattokinase. Additionally, it does not contain any vitamin K2 that would reduce the efficacy of the product. It provides the nattokinase in a gel capsule that contains gelatin and is therefore not vegan. Additionally, it should be noted that this product is not made in the USA.
When reviewing this product, we were pleased to see a price tag that suggests quality, but remains affordable. We appreciated that this product, like our top pick, is backed by a 60-day money back guarantee. However, unlike our top pick, this nattokinase supplement does not include a bioavailability enhancer to support the product’s efficacy. Continue reading our review for more about how this product compares.
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Rating: OK

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Ortho Molecular Products Nattokinase
Ortho Molecular Products Nattokinase claims to be an effective nattokinase supplement that supports normal blood flow and circulation, and maintains blood pressure in the normal range. The product itself is not supported by any reviews, but the company has a good reputation in the supplement world. Does this product have a formula to live up to its brand’s reputation?
Like our first two picks, this product provides the correct potency and dosage of nattokinase with 2000 FU per capsule. Unfortunately, there is no statement made about the removal of vitamin K2 from the formula, which could have a negative impact on the product’s efficacy. Additionally, Ortho Molecular Products nattokinase does not contain a bioavailability enhancer to boost absorption.
The price tag on this product is significantly higher than that of our other picks, while the money-back guarantee is half the time of our other top picks, at only 30-days. Continue reading our full review for more insights into the pros and cons of this product.
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